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1.
Data Brief ; 52: 110027, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38328501

RESUMEN

A primary dataset capturing five distinct types of sheep activities in realistic settings was constructed at various resolutions and viewing angles, targeting the expansion of the domain knowledge for non-contact virtual fencing approaches. The present dataset can be used to develop non-invasive approaches for sheep activity detection, which can be proven useful for farming activities including, but not limited to, sheep counting, virtual fencing, behavior detection for health status, and effective sheep breeding. Sheep activity classes include grazing, running, sitting, standing, and walking. The activities of individuals, as well as herds of sheep, were recorded at different resolutions and angles to provide a dataset of diverse characteristics, as summarized in Table 1. Overall, a total of 149,327 frames from 417 videos (the equivalent of 59 minutes of footage) are presented with a balanced set for each activity class, which can be utilized for robust non-invasive detection models based on computer vision techniques. Despite a decent existence of noise within the original data (e.g., segments with no sheep present, multiple sheep in single frames, multiple activities by one or more sheep in single as well as multiple frames, segments with sheep alongside other non-sheep objects), we provide original videos and the original videos' frames (with videos and frames containing humans omitted for privacy reasons). The present dataset includes diverse sheep activity characteristics and can be useful for robust detection and recognition models, as well as advanced activity detection models as a function of time for the applications.

2.
Sci Data ; 10(1): 320, 2023 05 26.
Artículo en Inglés | MEDLINE | ID: mdl-37237014

RESUMEN

Gait datasets are often limited by a lack of diversity in terms of the participants, appearance, viewing angle, environments, annotations, and availability. We present a primary gait dataset comprising 1,560 annotated casual walks from 64 participants, in both indoor and outdoor real-world environments. We used two digital cameras and a wearable digital goniometer to capture visual as well as motion signal gait-data respectively. Traditional methods of gait identification are often affected by the viewing angle and appearance of the participant therefore, this dataset mainly considers the diversity in various aspects (e.g., participants' attributes, background variations, and view angles). The dataset is captured from 8 viewing angles in 45° increments along-with alternative appearances for each participant, for example, via a change of clothing. The dataset provides 3,120 videos, containing approximately 748,800 image frames with detailed annotations including approximately 56,160,000 bodily keypoint annotations, identifying 75 keypoints per video frame, and approximately 1,026,480 motion data points captured from a digital goniometer for three limb segments (thigh, upper arm, and head).


Asunto(s)
Marcha , Dispositivos Electrónicos Vestibles , Humanos , Movimiento (Física)
3.
IEEE/ACM Trans Comput Biol Bioinform ; 20(5): 2700-2711, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37018274

RESUMEN

Alzheimer's disease (AD) is a type of brain disorder that is regarded as a degenerative disease because the corresponding symptoms aggravate with the time progression. Single nucleotide polymorphisms (SNPs) have been identified as relevant biomarkers for this condition. This study aims to identify SNPs biomarkers associated with the AD in order to perform a reliable classification of AD. In contrast to existing related works, we utilize deep transfer learning with varying experimental analysis for reliable classification of AD. For this purpose, the convolutional neural networks (CNN) are firstly trained over the genome-wide association studies (GWAS) dataset requested from the AD neuroimaging initiative. We then employ the deep transfer learning for further training of our CNN (as base model) over a different AD GWAS dataset, to extract the final set of features. The extracted features are then fed into Support Vector Machine for classification of AD. Detailed experiments are performed using multiple datasets and varying experimental configurations. The statistical outcomes indicate an accuracy of 89% which is a significant improvement when benchmarked with existing related works.


Asunto(s)
Enfermedad de Alzheimer , Imagen por Resonancia Magnética , Humanos , Imagen por Resonancia Magnética/métodos , Enfermedad de Alzheimer/diagnóstico por imagen , Enfermedad de Alzheimer/genética , Estudio de Asociación del Genoma Completo , Neuroimagen/métodos , Máquina de Vectores de Soporte , Biomarcadores
4.
IEEE/ACM Trans Comput Biol Bioinform ; 17(5): 1535-1545, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31634840

RESUMEN

Epistasis is a progressive approach that complements the 'common disease, common variant' hypothesis that highlights the potential for connected networks of genetic variants collaborating to produce a phenotypic expression. Epistasis is commonly performed as a pairwise or limitless-arity capacity that considers variant networks as either variant vs variant or as high order interactions. This type of analysis extends the number of tests that were previously performed in a standard approach such as Genome-Wide Association Study (GWAS), in which False Discovery Rate (FDR) is already an issue, therefore by multiplying the number of tests up to a factorial rate also increases the issue of FDR. Further to this, epistasis introduces its own limitations of computational complexity and intensity that are generated based on the analysis performed; to consider the most intense approach, a multivariate analysis introduces a time complexity of O(n!). Proposed in this paper is a novel methodology for the detection of epistasis using interpretable methods and best practice to outline interactions through filtering processes. Using a process of Random Sampling Regularisation which randomly splits and produces sample sets to conduct a voting system to regularise the significance and reliability of biological markers, SNPs. Preliminary results are promising, outlining a concise detection of interactions. Results for the detection of epistasis, in the classification of breast cancer patients, indicated eight outlined risk candidate interactions from five variants and a singular candidate variant with high protective association.


Asunto(s)
Epistasis Genética/genética , Genómica/métodos , Polimorfismo de Nucleótido Simple/genética , Inteligencia Artificial , Neoplasias de la Mama/genética , Femenino , Marcadores Genéticos/genética , Estudio de Asociación del Genoma Completo , Humanos , Modelos Logísticos , Fenotipo
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